Scientific publications in 2024 with support from the Borje Salming ALS Foundation
The Borje Salming ALS Foundation supports five prominent ALS researchers at Karolinska Institutet, the Royal Institute of Technology, Umeå University and the University of Gothenburg. Here you can read the reports that the researchers have published with the help of the foundation's support.
Anneli Ozanne
Adolescents’challenging and grief-filled transitions when living with a parent with ALS: Aqualitative interpretive study Malmström N, Öhlén J, Jakobsson Larsson B,Nilsson S, Nygren I, Andersen P M, Ozanne A. Social Science & Medicine 354(2024) 117063.
The use of the Strengths and Difficulties Questionnaire to assess mental healthin adolescents with parents diagnosed with Amyotrophic Lateral Sclerosis.Nilsson S, Malmström N, Nygren I, Öhlén J, Jakobsson Larsson B, Ozanne A.INTERNATIONAL JOURNAL OF ADOLESCENCE AND YOUTH. 2025, VOL. 30, NO. 1, 2454991.
https://doi.org/10.1080/02673843.2025.2454991
Per Zetterström
Data from the project on early aggregation of SOD1 in model systems were presented as a poster at the largest international meeting on ALS: the 35th International Symposium on ALS/MND held in Montreal, Canada.
Early aggregation and spreading of hSOD1 aggregates in ALS model mice
C. Henne, T. Brännström and P. Zetterström
Department of Medical Biosciences, Umeå University
Abstract for this poster is published here:
Theme 6 Tissue Biomarkers. (2024). Amyotrophic Lateral Sclerosis andFrontotemporal Degeneration, 25(sup1), 185–196.
https://doi.org/10.1080/21678421.2024.2403303
Caroline Ingre
Yazdani S, Lovik A, Seitz C, Ingre C, Fang F, Andersson J. T cell subset composition differs between blood and cerebrospinal fluid in amyotrophic lateral sclerosis. Clin Immunol. 2024 Aug;265:110270. doi: 10.1016/j.clim.2024.110270. Epub 2024Jun 7. PMID: 38852806.
Hu Y, Deeba E, Kläppe U, Öijerstedt L, Andersson J, Ruffin N, Piehl F, Ingre C, Fang F, Seitz C. Immune cells and the trajectories of depression, anxiety, and cognitive function among people with amyotrophic lateral sclerosis. Brain Behav Immun Health. 2024 Nov 22;42:100907. doi: 10.1016/j.bbih.2024.100907. PMID: 39650285; PMCID: PMC11625338.
Oral presentation, ENCLAS Stockholm, June 2024. "Longitudinal analysis of T cell responses in ALS"
Karin Forsberg
Roos AK, Stenvall E, Kockum ES, Grönlund KÅ, Alstermark H, Wuolikainen A, Andersen PM, Nordin A, Forsberg K. Small striatal huntingtin inclusions in patients withmotor neuron disease with reduced penetrance and intermediate HTT gene expansions. Hum Mol Genet. 2024 Nov 8;33(22):1966-1974.
Forsberg K, Karlsborg M, Salvesen L, Svenstrup K, Winroth I, Berntsson H, MAndersen P. Precisionsmedicinsk genterapi har bromsat utveckling av ALS [SOD1 gene therapy delays ALS disease progression]. Lakartidningen. 2024 Apr 26;121:24044.
Anna Månberg
Olofsson Jennie, Bergström Sofia, Mravinacová Sára, Kläppe Ulf, Öijerstedt Linn, Zetterberg Henrik, Blennow Kaj, Ingre Caroline, Nilsson Peter, Månberg Anna. Cerebrospinal fluid levels of NfM in relation to NfL and pNfH as prognosticmarkers in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener. 2025 Feb;26(1-2):113-123. doi:10.1080/21678421.2024.2428930. Epub 2024 Nov 22. PMID: 39575564.
Poster on ENCALS, June 2024 in Stockholm, Olofsson Jennie, Bergström Sofia, Mravinacová Sára, Kläppe Ulf, Öijerstedt Linn, Zetterberg Henrik, Blennow Kaj, Ingre Caroline, Nilsson Peter, Månberg Anna.
Title: Cerebrospinal fluid levels of NfM in relation to NfL and pNfH asprognostic markers in amyotrophic lateral sclerosis
Arbetet presenterades även som en del i Anna Månbergs publika docentföreläsning i november 2024 och på ett minisymposium på Karolinska Institutet med temat ”In-vivo approaches to understand neurodegenerative diseases” i oktober.
The work was also presented as part of Anna Månberg's public docent lecture in November 2024 and at a mini-symposium at Karolinska Institutet with the theme "In-vivo approaches to understand neurodegenerative diseases" in October.